KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
APC
All Species:
9.39
Human Site:
S1072
Identified Species:
17.22
UniProt:
P25054
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P25054
NP_000029.2
2843
311646
S1072
Q
R
Q
S
R
N
Q
S
T
T
Y
P
V
Y
T
Chimpanzee
Pan troglodytes
XP_001143509
2844
311637
S1072
Q
R
Q
S
R
N
Q
S
T
T
Y
P
V
Y
T
Rhesus Macaque
Macaca mulatta
XP_001095216
2303
243755
G581
C
Q
V
D
G
A
L
G
F
L
V
S
T
L
T
Dog
Lupus familis
XP_536285
2273
247246
N551
V
G
S
N
H
G
I
N
Q
N
V
N
Q
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q61315
2845
311071
N1070
Q
R
Q
A
R
S
Q
N
T
S
Y
P
V
Y
S
Rat
Rattus norvegicus
P70478
2842
310514
N1070
Q
R
Q
S
R
S
Q
N
T
N
F
P
V
Y
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511806
2844
309621
S1076
Q
R
Q
S
R
G
P
S
T
T
Y
P
G
Y
G
Chicken
Gallus gallus
XP_001233411
2232
244958
F510
M
A
L
T
N
L
T
F
G
D
V
A
N
K
A
Frog
Xenopus laevis
P70039
2829
310863
K1072
Q
R
Q
P
R
T
T
K
T
T
Y
S
S
Y
T
Zebra Danio
Brachydanio rerio
NP_001137312
2754
301074
Q1018
E
Q
L
N
S
G
R
Q
S
P
S
Q
N
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477152
2417
261266
H694
A
S
S
S
S
R
R
H
P
A
P
R
L
T
R
Honey Bee
Apis mellifera
XP_624558
2760
306907
E1036
Y
F
T
N
N
D
Q
E
L
I
H
E
D
T
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783363
3212
346162
T1165
F
V
Q
T
S
L
E
T
N
T
G
G
T
V
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
35
74.2
N.A.
90.4
90.1
N.A.
86.7
67.1
75
68
N.A.
23.8
22.8
N.A.
29.1
Protein Similarity:
100
99.5
49.4
76.1
N.A.
94.2
94.3
N.A.
92.7
72.2
84
78.2
N.A.
41
42
N.A.
45.1
P-Site Identity:
100
100
6.6
0
N.A.
66.6
66.6
N.A.
73.3
0
60
0
N.A.
6.6
6.6
N.A.
13.3
P-Site Similarity:
100
100
13.3
13.3
N.A.
100
93.3
N.A.
73.3
6.6
60
33.3
N.A.
20
26.6
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
8
0
8
0
0
0
8
0
8
0
0
8
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
8
0
0
0
8
0
0
8
0
0
% D
% Glu:
8
0
0
0
0
0
8
8
0
0
0
8
0
8
0
% E
% Phe:
8
8
0
0
0
0
0
8
8
0
8
0
0
0
0
% F
% Gly:
0
8
0
0
8
24
0
8
8
0
8
8
8
0
8
% G
% His:
0
0
0
0
8
0
0
8
0
0
8
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
8
0
0
8
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
8
0
0
0
0
0
8
0
% K
% Leu:
0
0
16
0
0
16
8
0
8
8
0
0
8
8
8
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
24
16
16
0
24
8
16
0
8
16
0
0
% N
% Pro:
0
0
0
8
0
0
8
0
8
8
8
39
0
0
0
% P
% Gln:
47
16
54
0
0
0
39
8
8
0
0
8
8
0
0
% Q
% Arg:
0
47
0
0
47
8
16
0
0
0
0
8
0
0
16
% R
% Ser:
0
8
16
39
24
16
0
24
8
8
8
16
8
8
16
% S
% Thr:
0
0
8
16
0
8
16
8
47
39
0
0
16
16
31
% T
% Val:
8
8
8
0
0
0
0
0
0
0
24
0
31
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
39
0
0
47
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _